Neurodegenerative Disease

The Effects of Low Dopamine Levels

Our bodies are so interesting, and it’s so fascinating how different chemicals produced in the brain affect our mood and outlook on life. Our individual brain chemistry is affected by many different factors, and when we don’t have enough of certain neurotransmitters, if our body isn’t making enough, it can really affect us, often being experienced as depression or anxiety.

I’m glad that the stigma against mental health issues has been changing in the past number of years. For the majority of people, depression and mental health problems are the result of imbalances in the naturally produced chemicals in the brain, through no fault of their own. Natural products or pharmaceuticals that help to remedy or boost those mood enhancing neurotransmitters can really help.

Of course I’d recommend trying natural products first, but sometimes a prescription might be needed, and that‘s fine, it’s important to do what’s best for your health. I’d recommend natural products first because they are generally free from side effects and can be stopped at any time without causing a problem (you need to be careful with many pharmaceuticals for depression, it’s not recommended that you just stop taking those drugs abruptly without a doctor’s recommendation).

The two main “feel good” neurotransmitters in the brain are serotonin and dopamine. Both are critical for proper brain function and mood. Serotonin is a little more involved with how we process emotions, whereas dopamine is also involved with mood, but it’s more focused on feelings of wellbeing, pleasure, and motivation.

For boosting serotonin, the amino acid 5-HTP as well as the herb saffron can be helpful and effective. 5-HTP has also been researched for helping with reducing stress and migraines in addition to helping with boosting mood. 5-HTP is not recommended to be used along with certain prescription antidepressants since it works in a similar way.

For dopamine levels, things can be a little trickier. When we are young, the body produces abundant amounts of dopamine in the brain, which is why many of us look back on childhood as a carefree time. As we age, our levels of dopamine are reduced. By age 45 our natural dopamine levels are reduced by roughly 13% for each decade that passes. Low amounts of dopamine in the brain translate to a lower sense of wellbeing. Drugs like cocaine and opioids give the brain a rush of dopamine, which is part of why they are so addictive. Similarly, cigarette smoking also gives a dopamine rush, which is why they are so difficult to quit. Dopamine is involved with our reward system and addictive behaviors, and low dopamine levels in the brain can make it even more likely for those people to seek out risky behaviors to feel that rush or increase in dopamine in the brain.

I am certainly not advocating any of the things above, but rather am just trying to explain how dopamine works. There are supplements that can boost dopamine, but I would not recommend them due to side effects (which is why we don’t carry them at our store). There is a natural supplement I would recommend, however,  that is involved with our bodies levels of dopamine, but it does it in a different way than just artificially increasing dopamine (which I don’t think is  a good idea).

Recent research has found that a plant known as the Amur cork tree works to inhibit an enzyme in our body that depletes dopamine levels in the brain, called MAO-B (it has a longer name, but let’s just call it that). It’s an herb that’s been used safely for centuries in Asia, but now science is confirming its wide reaching benefits, including its ability to help stabilize dopamine levels in the brain. Unlike things (primarily negative like drugs, cigarettes, and alcohol) that temporarily boost dopamine levels in the brain, extracts of the Amur cork tree, known as Phellodendron amurense, work to naturally increase overall levels of dopamine in the brain to levels comparable to when a person was younger, before the MAO-B enzyme levels increased that lower our brain’s amounts of available dopamine. That plant extract is not well known in America, but we’ve found a product by Life Extension that is a good source of it called Dopamine Advantage.

In addition to helping with higher overall dopamine levels in the brain, inhibiting the MAO-B enzyme in the body can also have brain protective effects.

There are prescription drugs that influence that dopamine enzyme that have been used for many years as a treatment for Parkinson’s disease (patients with Parkinson’s disease can have extremely low dopamine levels, in fact, low dopamine levels are thought to be one of the contributing factors in Parkinson’s disease). The Dopamine Advantage supplement I mentioned above works in a similar way, but naturally. Another nice thing is that the recommended amounts to be found effective in research is available in just one pill a day, and it’s also very reasonably priced (we have it for sale for $13.99 for a month’s supply- I love it when companies don’t price gouge, especially when they have a unique supplement that’s not found many places).

Please stop by Pass Health Foods for more information or if you have any questions. Everyone is different in their individual needs, and especially for issues like depression and anxiety, it’s not always “one size fits all”. Luckily, there are a lot of natural products that can really make a difference, and we are extremely knowledgeable about the various supplements for boosting mood and reducing stress and anxiety.

 

Probiotics for Disease Prevention [New Research]

I wanted to briefly write about probiotics since in the past few months, numerous new studies have come out showing previously unknown benefits of probiotics for disease prevention. I’ll link a few of the articles below:

New research underscores the link between multiple sclerosis and the gut microbiome

Gut bacteria trigger immune defense mechanism to protect against viral infections

Gut microbiome link to deadly chronic obstructive pulmonary disease

Study offers "indisputable" link between Alzheimer's and gut microbiome

Microbiome study could change the way doctors diagnose depression

We don’t often think of our digestive system unless it’s giving us trouble, and then usually we’re just looking for a fix for those symptoms, but our digestive system and specifically our body’s unique microbiome (or the trillions of bacteria and microorganisms that live in our digestive tract) affect our health far beyond our stomach.

A healthy balance and variety of good bacteria in the body is incredibly important for overall health, but it’s easy to be ignored since many people can take probiotics and not feel very different. Part of the benefit of probiotics are more overreaching, affecting our health long term for the better. It’s similar to giving a car an oil change- generally, the car doesn’t drive very differently after having one done, but it’s important to keep the vehicle running properly in the long run.

We have lots of great supplements at the store, which have benefits for an assortment of issues, but realistically a person can’t take 100 pills a day. So as you choose the supplements that are most important to your personal health, we’d really recommend adding (or continuing to take) a quality probiotic with a variety of well-researched strains. Stop by the store because we’d love to help you choose the product that’s best for you. A favorite of mine are Solaray’s line of refrigerated Mycrobiome probiotics. They have specific formulas for a variety of needs including a women’s probiotic, a 50+ formula, and one specifically for colon health. I like them because in addition to being high potency products with a variety of effective probiotic strains, they also contain prebiotics, which help the good bacteria in your digestive tract and in the supplements you take to flourish.

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New Research: Probiotics May Help to Prevent Neurodegenerative Diseases

I’ve written numerous times about probiotics and their benefits to so many aspects of our health (here’s a good overview on probiotics on our website).

Probiotics help with digestion, the immune system, and reducing antibiotic side effects, though specific strains can be beneficial for IBS, vaginal health, gum disease, and more.

New research has come out linking probiotics and a varied microbiome as a preventative measure against a variety of neurodegenerative diseases.

Neurodegenerative diseases like Alzheimers, multiple sclerosis, and Parkinson’s disease are scary, since their onset can be unpredictable, and so much is still unknown about these uncurable diseases.

Scientists have begun to link viral infection as a possible cause of various neurodegenerative diseases (here’s a link to research on Pub Med), and have also linked good bacteria in the gut and a varied microbiome as a possibly preventative to the triggering of neurodegenerative diseases.

The colonization of good bacteria in our bodies known as our microbiome is still not yet completely understood, though now scientists are finding far reaching benefits probiotics and of maintaining a thriving and varied microbiome in our bodies, not just for digestion and the immune system, but also for mood, inflammation, and so much more.

Supplementing with probiotics is something I absolutely believe in, particularly when using a quality probiotic with a good potency and a nice variety of different strains. Different strains of probiotics, or good bacteria, work in different ways in the body, so choosing a probiotic supplement with a diverse makeup is always a good idea.

We have just brought in a new probiotic that I wanted to highlight from a company called Vital Planet, that has a line of probiotics available in both refrigerated and shelf stable varieties at high potency. Their probiotics come in a variety of specific formulas, including some formulated specifically for men or women, and contain 60 billion probiotics per capsule from 60 different strains that also include probiotics, to help those good bacteria to thrive in the body. I’ve been using their Women’s Shelf Stable Probiotic and I really like it.

Our Vital Planet Probiotics will be on sale through the month of September for 25% off, so it’s a great time to try them. We also have a limited amount of $3 off coupons at the store, which make it an even better deal, so stop by to check them out!

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