Hair Loss

A New Supplement for Female Hair Loss [New Research]

Hair loss and hair thinning in women is very common, especially as women near menopause. It’s suggested that it’s often caused by hormonal changes, which makes sense. Thinning hair can be really upsetting to deal with, and can sometimes be difficult to treat. I came across some new research I wanted to share about hair loss in women. I was pretty impressed by the study, so I wanted to share the information in case it helps anyone.

The study was on the antioxidant pycnogenol, which is an extract from French maritime pine bark (pronounced pick-nodge-eh-nol) that measured hair density in menopausal women. Hair density if a useful way to study hair thinning since it literally means counting the amount of hairs in a specific measured area.

The study consisted of women aged 45-60 and measured how many hairs they had in a specific square centimeter on their heads, which averaged 225.8 hairs at the beginning of the study. After two months of taking pycnogenol at a dose of 150mg a day broken up into three 50mg doses, the average women’s hair density increased from 225.8 hairs in one square centimeter to 293.6 hairs after two months of taking pycnogenol, a 30% increase. The women in the placebo group did not experience a significant change in their hair density. That sounds pretty impressive to me. The study also measured that the women who took pycnogenol had increased scalp circulation- poor blood circulation in the scalp is associated with hair loss.

I certainly don’t mean to put the supplement pycnogenol forward as a miracle for female hair loss, but the research is definitely impressive. I’ve spoken to many women who have come into the health food store who are anxious about hair loss, so this does seem like something to try. I’d also say that for the vast majority of women who I’ve spoken to who are worried about their own hair loss, that it usually doesn’t seem very noticeable to me. I do think we’re the most critical of ourselves, where we may feel lacking in some way that we’re worried about, but then it often isn’t even noticed by anyone else.

Still, pycnogenol is an interesting supplement since it has so many different and seemingly unrelated benefits. It’s been shown to help with blood flow, both to the legs and for cardiovascular health, and is also often used to help with asthma symptoms in children and adults. One of the most impressive results of pycnogenol, other than this new research for hair loss, is for brain function in adults middle aged and older. I wrote about pycnogenol back in 2017 when the research came out, but the information is still relevant.

A year long, placebo controlled study on pycnogenol and brain function followed seventy-seven adults aged 55 to 70. Half the group was given 100 milligrams of pycnogenol daily, and at the end of the study, tests showed a seventy-two percent improvement in decision making in the pycnogenol group (vs. a five percent decline in the placebo group). The attention span of the group that took pycnogenol was increased by forty-one percent and memory improved by thirty-seven percent (compared to a ten percent decline in the control group). 

Pycnogenol has also been shown to aid in lowering blood pressure, helping to normalize blood pressure readings in fifty-eight percent of hypertensive patients. Another study found that participants who took Pycnogenol were able to reduce their blood pressure medications after taking the supplement for 12 weeks.

Other double-blind studies have reported pycnogenol’s benefit for lowering blood sugar in patients with Type 2 diabetes. After twelve weeks of taking the French maritime pine bark extract, it was reported that the supplement, “significantly lowered plasma glucose levels” when compared with the placebo. Pycnogenol also improved blood flow and blood vessel health.

I really love supplements that have more than one different benefit, and I’d say pycnogenol definitely excels in that area. Something thing to keep in mind however, it that the majority of these studies are done over a decent period of time, ranging from two months to a year, so as with any supplement, it’s good to be patient and give it some time to work. Also, no matter how great a study says something is, nothing works 100% of the time for every single person. Still, I think pycnogenol is an impressive supplement that’s worth trying. It has a long safety record, but it’s always a good idea to tell your doctor or pharmacist of any supplements you’re taking in case of drug interactions. For example, pycnogenol shouldn’t be taken with prescription blood thinning medications because it has a slight blood thinning effect.

Stop by Pass Health Foods in Palos Heights if you have any questions, we’d love to help you further. We’re at 7228 W. College Drive in Palos Heights.

Biotin for Strong, Healthy Hair & Nails

I wanted to write about biotin this month, a B vitamin that is most well known for its benefit for hair and nails, and rightly so- it’s really amazing for strengthening the hair and nails as well as preventing hair loss.

The earliest research on biotin was done mainly with veterinary literature, where biotin was found to increase the strength and hardness of pigs and horses hooves. Those hooves are made of keratin, the same material our nails are made of, as well as our hair strands. The discovery that biotin made such a difference for the hooves (nails) of animals inspired the research to continue to humans.

Many of our customers have had great results for their hair and nails after supplementing with biotin that has also been confirmed by research studies in humans. One such study found that supplementing with biotin at a dose of 2500mcg a day increased the thickness of the human nail plate by 25%. Ninety-one percent of people taking that dosage experienced definite improvement in their nails, especially people who complained of weak, brittle nails before supplementation.

A deficiency in biotin can cause hair loss, and biotin supplementation has been linked to a reduction in hair loss and thinning hair. Other research has confirmed that biotin supplementation helps with brittle nails and thinning hair in people diagnosed with nail issues and poor hair growth. One 2015 study (linked here) found that 90 days of biotin supplementation helped women with hair loss to increase their hair density as well as reduce the shedding of hair. Additional studies have had participants report positive results on the appearance of hair and thickness after 90 days, which increased the longer that people took the biotin supplements.

In addition to biotin’s benefits for hair and nails, biotin can also be beneficial for cardiovascular health as well as increasing blood sugar sensitivity. Biotin appears to help increase the activity of specific liver enzymes that help the liver to utilize blood sugar. When those enzymes are activated, the liver is able to pull sugar from the blood to be properly metabolized. In one study, participants who took 8mg of biotin twice daily resulted in significant improvements in fasting blood sugar levels and blood sugar control in type 1 diabetics. Other research has reported that biotin combined with chromium (a mineral that can help with balancing blood sugar) was effective in reducing blood sugar levels as well as lowering triglyceride levels in the blood of type 2 diabetes patients.

High dose biotin supplementation has also been researched in some very groundbreaking studies on multiple sclerosis, though the research is still in its early stages. I just wanted to mention it since it’s always exciting when vitamins that have been around forever are found to be beneficial in new, previously unknown ways.

Supplementing with biotin for hair and nails definitely has benefits, but keep in mind that it’s more of a long term thing (most studies were for at least 90 days), since it takes time to made a difference in hair and nail strength. Biotin is a water soluble B vitamin, which means that whatever the body does not use is excreted, making biotin an extremely safe supplement to take. High dose biotin can interfere with some blood tests (it’s not harmful, but something to be aware of), so it’s recommended to stop taking biotin for a week before a blood panel, or to mention your biotin supplementation to your physician (which is good advice for all supplements).
 

A New "Hair Loss" Enzyme for Men

Q: A friend sent me an article on the discovery of an enzyme that’s supposed to cause baldness in men. The article said that they are working on a medicine that will block the enzyme, but there were other natural things that could block it too. It’s supposed to be a miracle for male pattern baldness. I wondered if you’d heard of it and knew of anything that could block the enzyme and help with hair loss.

A: Several years ago, researchers at the University of Pennsylvania published a paper on the discovery of a new enzyme, called PGD2 that prevents hair follicles from maturing. It was found that balding men had much higher levels of this enzyme, which inhibits hair growth. A prescription blocker of the PGD2 enzyme is said to be in the works, but it is many years from being released.

There are some natural products which have been researched to block the same “hair loss” enzyme; quercetin, a compound found in citrus fruits, and resveratrol, an antioxidant found in red wine. Both have been found in research to be able to suppress the PGD2 enzyme which is linked to male hair loss. 

The research is very preliminary, however, and even though studies have found quercetin and resveratrol to be effective in inhibiting the PGD2 enzyme, it does not necessarily mean they will help prevent or reverse hair loss. Both supplements are safe and beneficial to take, however, and some men may decide to begin taking the supplements to see if they make a difference. Quercetin also has benefits for allergies and the immune system, and resveratrol is well know as a potent antioxidant with anti-inflammatory anti-aging properties.

So, yes, there are natural products that can block the “hair loss” enzyme, but I would be hesitant to call them a “miracle cure”. Still, there’s no harm in trying it, since they are supplements which have additional benefits for anyone.